treatfip.org

Niels C. Pedersen, DVM, PhDCenter for Companion Animal HealthUniversity of California, DavisJune 14, 2022 Origin of FIP effusions. Effusions of wet FIP originate from small, inflamed blood vessels (venules) within the tissue that lines the surfaces of abdominal and thoracic organs,mesenteries/mediastinum, and omentum. This thin tissue or membrane is called Read more…

Niels C. Pedersen DVM, PhD  October 20, 2021 Beta-d-N4-hydroxycytidine is a small molecule (nucleoside) that was studied in the late 1970s in the  old Soviet Union as part of biological weapons research [2]. Weaponization of diseases like smallpox was  a worldwide fear, but the dangers of using smallpox virus for this Read more…

NC. Pedersen, DVM PhD  March 23, 2022  Several questions frequently arise during FIP treatment. Before discussing these questions, it is  important to review the status of FIP treatment. Only antiviral drugs that target specific viral  proteins and inhibit replication of FIP virus have been shown to be curative. At present, Read more…

Niels C. Pedersen, Nicole Jacque  November 3, 2021 Introduction  Resistance to antiviral diseases has been well documented for diseases like HIV/AIDs and hepatitis C. In  some cases, this resistance is present in the infecting virus, but more frequently it is a result of  prolonged drug exposure. Resistance to both GC376 Read more…

Niels C. Pedersen, DVM PhD, Distinguished Professor Emeritus   Center for Companion Animal Health   School of Veterinary Medicine, UC Davis   We use the same criteria for monitoring treatment as described in the JFMS field trial paper.  Owners are asked to keep track of temperature, weight, activity, appetite, clinical signs of original  Read more…

Background– Feline leukemia virus (FeLV) is a retrovirus related to murine leukemia virus that has existed among feral cats for tens of thousands of years before its discovery in 1964 (Jarrett, et al., 1964). FeLV infection occurs mainly among cats under 3-8 years of age (reviewed Pedersen, 1998, 1991). The Read more…

Niels C. Pedersen, DVM PhD  June 1, 2021  Introduction – Neurological involvement occurs in about 5-10% of FIP cases.  This may vary between regions, as Turkish street cats appear to have a greater  incidence based on this author’s experiences. The age of onset parallels that of other forms of FIP, with Read more…

Introduction – Pregnancy is an interesting immunologic paradox. Although organs  and tissues from individuals of same (allograft) or different species (xenograft) are  recognized as foreign and destroyed, the fetus, which is an allograft, is not. Prevention of fetal rejection is accompanied by events linked to the complex  hormonal changes that are Read more…

Niels C. Pedersen, DVM PhD April 6, 2021 The use of supplements for dogs and cats has become increasingly more common, mirroring the increase in the use of supplements for people. I have also noticed that many owners of cats are using numerous supplements to augment treatment GS-441524 treatment for Read more…

February 11, 2021 Background: The relationship of age and FIP incidence has been well discussed in the literature and has even been the topic of research [1]. Twenty-nine percent of FIP cases occurs in kittens under 0.5 years of age, 50% under 1.0 years, 80% less than 3.0 years, and Read more…